Retatrutide

pues eso:

resumen del ensayo TRIUMPH-1: con una dosis de 12 mg durante 80 semanas, los pacientes perdieron una media del 28,3 % de su peso corporal

no hay que olvidar de dónde venimos:

Glucagon-like peptide-1 gene therapy in obese diabetic mice results in long-term cure of diabetes by improving insulin sensitivity and reducing hepatic gluconeogenesis

aunque hay este otro método, que parece que también funciona (perdió 126kg):

Angus Barbieri - wikipedia

aunque la muestra es pequeña, y están por ver los efectos (perder un 30% de masa tampoco es muy "normal")..

pues eso:

Eli Lilly released retatrutide Phase 3 data yesterday. 28% weight loss in 80 weeks. The most powerful obesity drug that’s ever been tested.

And today the cancer signal drops.

12,112 patients. Seven tumor types. GLP-1 users had half the lung cancer metastasis rate (10% vs 22%).… https://t.co/wqMGXWckw0

— Avi Roy (@agingroy) May 22, 2026

These numbers are shocking. It's like we got a new frontier AI model but for the body.

Lilly's phase 3 results for retatrutide:

> highest dose lost 28.3% of body weight in 80 wks
> 70 lbs ave
> 45% lost 30% or more of their body weight
> 65% on the top dose no longer… pic.twitter.com/MEpzaRKYZ9

— Bryan Johnson (@bryan_johnson) May 22, 2026

Everyone is talking about Eli Lilly's retatrutide results in the pivotal phase 3 obesity trial.

This is the proper breakdown, in full: (1/13) pic.twitter.com/CMFIGeExYd

— Real Peptides (@realpeptides) May 22, 2026